HALO® Knowledge

UHPLC separation
A fast separation is achieved by smaller size particles in the column which reduces the diffusion of solutes into and out of the stationary phase and therefore reduces peak broadening. This allows faster flow rates, fast separations and higher sample throughput. Unfortunately the smaller particles increase back pressure excessively and "fast" columns usually require expensive ultra-high pressure instrumentation.

HALO^® Fused-Core columns
With the Fused-Core particle technology a porous shell is fused to a solid core particle. The shorter diffusion path of the HALO^® particles reduces axial dispersion of solutes and minimises peak broadening, which, compared to a totally porous particle, allows faster flow rates at a "regular" pressure.
Because of the increased separation power of the HALO^® column, it can either be used for faster analysis or an improved separation.

About Fused-Core^® Technology

• Modernise USP-Methoden for faster results & solvent saving

HALO^® - Small Molecules

• Can your stationary phase be used under 100% aqueous conditions?

HALO^® PCS: New Column Chemistry Options for Basic Compounds

Download White Paper

• HALO^® PCS: New Column Chemistry Options for Basic Compounds
• Reversed Phase Positive Charge Surface Phenyl-Hexyl Phase for Improved Separations of Basic Analytes

Download Technical Documents

• Improved Bioseparations with HALO^® PCS C18 PEPTIDE
• What to Expect from HALO® PCS C18

HALO^® Enviroclass - for Environmental Analysis

• Environmental Analyses of Harmful Chemical and Organic Compounds using Superficially Porous Particle Separations

• Introducing HALO^® PAH

• An examination of PFAS analysis using LCMS for EPA methods 537.1 and EPA 8327 using HALO^® Fused-Core^® Technology

• The Analysis of PFAS in bottled water