HALO® - small molecules

HALO^® columns offer a solution for each separation challenge, be it the separation of a few compounds or a complex natural product sample containing hundreds of analytes.

For small molecule analyses (MW < 1000), HALO^® columns are available in three different particle sizes: 2 µm, 2.7 µm, and 5 µm.

Details on the individual particle sizes are described in the tabs below.

Highest UHPLC performance possible without the disadvantages of sub-2 μm columns

Use when the highest efficiency is needed
Excellent for fast method development and column/condition screening
Best performance obtained with instrumentation having extracolumn volume (IBW< 10 μL)
Ruggedness for R&D
1 μm inlet frit
Pressure limit, 1000 bar/14,500 psi

Reliable, efficient performance with lower back pressure compared to all sub-2 μm columns.

Use for high speed or high resolution with UHPLC or HPLC applications
Excellent for R&D and routine analyses
2 μm inlet frit
Pressure limit, 600 bar/9000 psi

Performance of 3 μm non-core column at 5 μm column pressures:

QC laboratories
Dirty samples
High throughput, ballistic gradient and isocratic applications
High resolution at HPLC back pressures (using columns in series)
2 μm inlet frit
Pressure limit, 600 bar/9000 psi