HALO® - small molecules

HALO® columns offer a solution for each separation challenge, be it the separation of a few compounds or a complex natural product sample containing hundreds of analytes.

For small molecule analyses (MW < 1000), HALO® columns are available in three different particle sizes: 2 µm, 2.7 µm, and 5 µm.

Details on the individual particle sizes are described in the tabs below.

Highest UHPLC performance possible without the disadvantages of sub-2 μm columns

  • Use when the highest efficiency is needed
  • Excellent for fast method development and column/condition screening
  • Best performance obtained with instrumentation having extracolumn volume (IBW< 10 μL)
  • Ruggedness for R&D
  • 1 μm inlet frit
  • Pressure limit, 1000 bar/14,500 psi

Reliable, efficient performance with lower back pressure compared to all sub-2 μm columns.

  • Use for high speed or high resolution with UHPLC or HPLC applications
  • Excellent for R&D and routine analyses
  • 2 μm inlet frit
  • Pressure limit, 600 bar/9000 psi

Performance of 3 μm non-core column at 5 μm column pressures:

  • QC laboratories
  • Dirty samples
  • High throughput, ballistic gradient and isocratic applications
  • High resolution at HPLC back pressures (using columns in series)
  • 2 μm inlet frit
  • Pressure limit, 600 bar/9000 psi

 


Phase
HILIC
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
C18
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
ES-CN
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
Penta-HILIC
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
Phenyl-Hexyl
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
RP-Amide
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
C8
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
PFP
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
Biphenyl
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
AQ-C18
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.5 mm
Length
150 mm

Phase
HILIC
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.3 mm
Length
50 mm

Phase
C18
Particle size
2.7 µm
Pore size
90 Å
Inner Diameter
0.3 mm
Length
50 mm